A year-old woman was admitted to our department with a history of itching and pain of the vulvar region. During a period of 6 months, her clinical symptoms had significantly deteriorated resulting in painful urination and defecation in addition to dyspareunia. Clinical examination showed well-demarcated, smooth, whitish shiny plaques that affected the labia minora, introitus vaginae, and the clitoral hood. Lesions extended to the posterior fourchette, perineum, and anus. The mucosa appeared thin and fragile with a cellophane paper—like texture. The clinical picture suggested a diagnosis of lichen sclerosus.
Successful Treatment of Vulvar Lichen Sclerosus With Topical Tacrolimus
Lichen Sclerosus - NORD (National Organization for Rare Disorders)
Lichen sclerosus is a skin condition. The condition can affect any part of your body, but it most commonly affects skin in the genital and anal regions. Lichen sclerosus is most common on the vulvas of women. The areas of skin may also be slightly raised. Because the affected areas are often around the vulva and genital, they may not be noticed unless other symptoms occur. Because the skin affected by lichen sclerosus is thinner than normal, it can bruise or blister more easily. In severe cases, it can result in ulcerated lesions, or open wounds.
Rare Disease Database
Lichen sclerosus LIE-kun skluh-ROW-sus is an uncommon condition that creates patchy, white skin that appears thinner than normal. It usually affects the genital and anal areas. Your doctor can suggest treatment with creams or ointments that help return a more normal appearance to your skin and decrease the tendency for scarring. The condition does tend to recur, so long-term follow-up care may be needed.
Lichen sclerosus is a chronic inflammatory skin condition that most commonly affects the vulva, groin, and perianal region of postmenopausal women. The estimated prevalence ranges from 1 in 30 elderly women to 1 in 1, patients referred to a dermatologist. Because these patients may initially present at the onset of symptoms to a wide variety of practices such as primary care, dermatology, gynecology, urology, pediatrics, or even the emergency department, it is important for practitioners to understand how to properly diagnose and treat those with this disease. Severe cases of vulvar lichen sclerosus can significantly impair the quality of life that patients have, as it often negatively affects women physically, mentally, and emotionally.